Current activities
GitHub
Publications
Doctoral thesis
Proceedings, articles, reports
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Hellen Lesmann, Tom Kamphans, Peter Krawitz, Tzung-Chien Hsieh et. al.
GestaltMatcher Database - a FAIR database for medical imaging data of rare diseases
Abstr. ACMG Ann. Clincal Genetics Meeting, 2023.
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Tzung-Chien Hsieh, Luisa Averdunk, C. C. Mak, Tom Kamphans, Wolfgang Meiswinkel, Peter M. Krawitz
GestaltMatcher research platform facilitates the novel gene-phenotype explora
Proc. 32nd Annual Meeting of the German Society of Human Genetics, 2022, pp. 8.
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Tzung-Chien Hsieh, Aviram Bar-Haim, Shahida Moosa, et al.
GestaltMatcher facilitates rare disease matching using facial phenotype descriptors
Nature Genetics, pp. 349-357, 2022.
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Chengyao Peng, Simon Dieck, Alexander Schmid, Ashar Ahmad, Alexej Knaus, Maren Wenzel, Laura Mehnert, Birgit Zirn, Tobias Haack, Stephan Ossowski, Matias Wagner, Theresa Brunet, Nadja Ehmke, Magdalena Danyel, Stanislav Rosnev, Tom Kamphans, Guy Nadav, Nicole Fleischer, Holger Fröhlich, Peter Krawitz
CADA: phenotype-driven gene prioritization based on a case-enriched knowledge graph
NAR Genomics and Bioinformatics 3(3), 2021.
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Hsieh, Tzung-Chien, Bar-Haim, Aviram, Moosa, Shahida, Ehmke, Nadja, Gripp, Karen W., Pantel, Jean Tori, Danyel, Magdalena, Mensah, Martin Atta, Horn, Denise, Fleischer, Nicole, Bonini, Guilherme, Schmid, Alexander, Knaus, Alexej, Sivalingam, Sugirthan, Kamphans, Tom, Ebstein, Frédéric, Krüger, Elke, Küry, Sébastien, Bézieau, Stéphane, Schmidt, Axel, Peters, Sophia, Engels, Hartmut, Mangold, Elisabeth, Kreiß, Martina, Cremer, Kirsten, Perne, Claudia, Betz, Regina C., Grundmann-Hauser, Kathrin, Haack, Tobias, Wagner, Matias, Brunet, Theresa, Bentzen, Heidi Beate, Spielmann, Malte, Schaaf, Christian, Mundlos, Stefan, Nöthen, Markus M., Krawitz, Peter
GestaltMatcher: Overcoming the limits of rare disease matching using facial phenotypic descriptors
medRxiv, 2021.
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T. Hsieh, A. Bar-Haim, D. Dukic, T. J. Pantel, M. Mensah, Y. Gurovich, N. Fleischer, Y. Hanani, T. Kamphans, G. Nadav, P Krawitz
GestaltMatcher: Identifying the second patient of its kind in the phenotype space
Europ J Human Genetics 27, pp. 1159-1159, 2019.
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Tzung-Chien Hsieh, Peter Krawitz, et al
PEDIA: prioritization of exome data by image analysis
Genetics in Medicine, pp. 2807-2814, 2019.
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Jean T. Pantel, Max Zhao, Martin A. Mensah, Nurulhuda Hajjir, Tzung-Chien Hsieh And Yair Hanani, Nicole Fleischer, Tom Kamphans, Stefan Mundlos, Yaron Gurovich, Peter M. Krawitz
Advances in computer-assisted syndrome recognition by the example of inborn errors of metabolism
J Inherit Metab Dis, pp. 1-7, 2018.
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Jean T. Pantel, Max Zhao, Martin A. Mensah, Nurulhuda Hajjir, Tzung-Chien Hsieh, Yair Hanani, Nicole Fleischer, Tom Kamphans, Stefan Mundlos, Yaron Gurovich, Peter M. Krawitz
Advances in computer-assisted syndrome recognition by the example of inborn errors of metabolism
Abstr. Europ. Human Genetics Conf., 2018, pp. P16.17A / A.
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Tzung-Chien Hsieh, Nurulhuda Hajjir, Jean T. Pantel, Martin A. Mensah, Max Zhao, Jacob Hertzberg, Max Schubach, Sebastian Köhler, Yaron Gurovich, Nicole Fleischer, Hilda David-Eden, Yair Hanani, Tom Kamphans, Denise Horn, Stefan Mundlos, Peter M. Krawitz
Exploring molecular interactions by clustering analysis of similarity scores from next-generation phenotyping approaches
Abstr. Europ. Human Genetics Conf., 2018, pp. P16.40D.
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Verena Heinrich, Tom Kamphans, Stefan Mundlos, Peter N. Robinson, Peter M. Krawitz
A likelihood ratio-based method to predict exact pedigrees for complex families from next-generation sequencing data
Bioinformatics 33(1), pp. 72-78, 2017.
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Jean Tori Pantel, Max Zhao, Martin Atta Mensah, Nurulhuda Hajjir, Tzung-Chien Hsieh, Yair Hanani, Nicole Fleischer, Tom Kamphans, Stefan Mundlos, Yaron Gurovich, Peter M. Krawitz
Advances in computer-assisted syndrome recognition and differentiation in a set of metabolic disorders
bioRxiv Genetics, 2017.
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Verena Heinrich, Tom Kamphans, Stefan Mundlos, Peter N. Robinson, Peter M. Krawitz
Prediction of complex pedigree structures from NGS data
27th Annual Meeting of the German Society of Human Genetics,
Medizinische Genetik 28, 2016, pp. 120.
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Verena Heinrich, Tom Kamphans, Peter N. Robinson, Peter M. Krawitz
"A likelihood ratio based method to predict exact pedigrees for
Abstracts European Human Genetics Conference,
Europ. J. Human Genetics 24, E-Suppl. 1, 2016, pp. 352.
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Zhu Na, Verena Heinrich, Thorsten Dickhaus, Jochen Hecht, Peter N. Robinson, Stefan Mundlos, Tom Kamphans, Peter M. Krawitz
Strategies to improve the performance of rare variant association studies by optimizing the selection of controls
Bioinformatics 31(22), pp. 3577-3583, 2015.
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Zhu Na, Verena Heinrich, Thorsten Dickhaus, Jochen Hecht, Peter N. Robinson, Stefan Mundlos, Tom Kamphans, Peter M. Krawitz
Strategies to improve the performance of rare variant rare disease association studies by optimizing the selection of controls
26th Annual Meeting of the German Society of Human Genetics,
Medizinische Genetik 27, 2015, pp. 97.
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Peter M. Krawitz, Tom Kamphans
How to find the second patient of its kind
26th Annual Meeting of the German Society of Human Genetics,
Medizinische Genetik 27, 2015, pp. 136.
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Sándor P. Fekete, Tom Kamphans, Nils Schweer
Online Square Packing with Gravity
Algorithmica 68, pp. 1019-1044, 2014.
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Verena Heinrich, Tom Kamphans, Jens Stange, Dmitri Parkhomchuk, Thorsten Dickhaus, Jochen Hecht, Stefan Mundlos, Peter N Robinson, Peter M Krawitz
Estimating exome genotyping accuracy by comparing to data from large scale sequencing projects
24th Annual Meeting of the German Society of Human Genetics,
Medizinische Genetik 25, 2013, pp. 174.
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Tom Kamphans, Peggy Sabri, Na Zhu, Verena Heinrich, Stefan Mundlos, Peter N. Robinson, Dmitri Parkhomchuk, Peter M. Krawitz
Filtering for Compound Heterozygous Sequence Variants in Non-Consanguineous Pedigrees
PLoS ONE 8(8), 2013.
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Tom Kamphans, Peggy Sabri, Verena Heinrich, Peter N. Robinson, Peter M. Krawitz
Filtering for compound heterozygous sequence variants in non-consanguineous pedigrees
Poster Abstr. 63th Annu. Meeting Am. Society of Human Genetics , 2013, pp. 323.
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Verena Heinrich, Tom Kamphans, Jens Stange, Dmitri Parkhomchuk, Thorsten Dickhaus, Jochen Hecht, Peter Nick Robinson, Peter M. Krawitz
Estimating Exome Genotyping Accuracy by Comparing to Data from Large Scale Sequencing Projects
Genome Medicine 2013 5:69, 2013.
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Tom Kamphans, Peter Krawitz, Peggy Sabri, Alexej Knaus
GeneTalk: a compound heterozygotes filter for exome data
Abstracts European Human Genetics Conference,
Europ. J. Human Genetics 21, Suppl. 2, 2013, pp. 369.
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Verena Heinrich, Tom Kamphans, Jens Stange, Dmitri Parkhomchuk, Thorsten Dickhaus, Jochen Hecht, Stefan Mundlos, Peter N Robinson, Peter M Krawitz
Estimating exome genotyping accuracy by comparing to data from large scale sequencing projects
Abstracts European Human Genetics Conference,
Europ. J. Human Genetics 21, Suppl. 2, 2013, pp. 375.
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Josef Angermeier, Sándor P. Fekete, Tom Kamphans, Dirk Koch, Nils Schweer, Jürgen Teich, Christopher Tessars, Jan C. van der Veen
Dynamic Defragmentation of Reconfigurable Devices
ACM Transact. Reconfig. Techn. Syst. 5 (2), 2012.
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Tom Kamphans, Peter M. Krawitz
GeneTalk: An expert exchange platform for assessing rare sequence variants in personal genomes
Bioinformatics 28 (19), pp. 2515-2516, 2012.
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Tom Kamphans, Peter M. Krawitz
GeneTalk: An expert exchange platform for assessing rare sequence variants in personal genomes
Poster Abstr. 62th Annu. Meeting Am. Society of Human Genetics, 2012.
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Tom Kamphans, Peter M. Krawitz
GeneTalk: An expert exchange platform for assessing rare sequence variants in personal genomes
Abstracts European Human Genetics Conference,
Europ. J. Human Genetics 20, Suppl. 1, 2012, pp. 280.
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Michael Stelzer, Jibin Sun, Tom Kamphans, Sándor P. Fekete, An-Ping Zeng
An extended bioreaction database that significantly improves reconstruction and analysis of genome-scale metabolic networks
Integrative Biology 3(11), pp. 1071-1086, 2011.
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Tobias Baumgartner, Sándor P Fekete, Tom Kamphans, Alexander Kröller, Max Pagel, Matthias Gietzelt, Reinhold Haux
Demo abstract: using a sensor network to enhance a standardized medical test
Europ. Conf. Wireless Sensor Networks, 2011.
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Sándor P. Fekete, Henning Hasemann, Tom Kamphans, Christiane Schmidt
Geometric Motion Planning: Finding Intersections
Abstracts 27th European Workshop Comput. Geom., 2011, pp. 189-192.
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Henning Hasemann, Tom Kamphans, Alexander Kröller
Searching for Radio Beacons with Mobile Agents that Perceive Discrete Signal Intensities
Abstracts 27th European Workshop Comput. Geom., 2011, pp. 159-162.
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Sándor P. Fekete, Tom Kamphans, Alexander Kröller, Joseph S.B. Mitchell, Christiane Schmidt
Exploring and Triangulating a Region by a Swarm of Robots
14th Internat. Workshop Approx. Algor. Combin. Optim. Prob.,
Lecture Notes Comput. Sci. 6845, Springer, 2011, pp. 206-217.
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Rolf Klein, Tom Kamphans
Pledge's Algorithm: How to Escape from a Dark Maze
In Algorithms Unplugged,
edited by Berthold Vöcking, Helmut Alt, Martin Dietzfelbinger, Rüdiger Reischuk, Christian Scheideler, Heribert Vollmer, Dorothea Wagner, Springer, 2011, pp. 69-75.
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Rudolf Fleischer, Tom Kamphans, Rolf Klein, Elmar Langetepe, Gerhard Trippen
The Tourist in the Shopping Arcade
J. Universal Comput. Sci. 16(5), pp. 676-685, 2010.
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Tobias Baumgartner, Sándor P. Fekete, Tom Kamphans, Alexander Kröller, Max Pagel
Hallway Monitoring: Distributed Data Processing with Wireless Sensor Network
Proc. 4th Workshop on Real-World Wireless Sensor Networks,
Lecture Notes Comput. Sci. 6511, 2010, pp. 94-105.
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Tom Kamphans, Elmar Langetepe
Leaving an unknown maze using an error-prone compass
Internat. J. Comput. Geom. Appl. 20, pp. 307-325, 2010.
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Josef Angermeier, Sándor P. Fekete, Tom Kamphans, Nils Schweer, Jürgen Teich
Virtual Area Management: Multitasking on Dynamically Partially Reconfigurable Devices
Proc. 17th Reconf. Architect. Workshop, 2010.
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Sándor P. Fekete, Tom Kamphans, Alexander Kröller, Christiane Schmidt
Robot Swarms for Exploration and Triangulation of Unknown Environments
Abstracts 26th European Workshop Comput. Geom., 2010, pp. 153-156.
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Tom Kamphans, Elmar Langetepe
Inspecting a set of strips optimally
Proc. 20th Algorithms and Data Structure Symposium (WADS),
Lecture Notes Comput. Sci. 5664, Springer, 2009, pp. 423-434.
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Tom Kamphans, Elmar Langetepe
Inspecting a set of strips optimally
Abstracts 25th European Workshop Comput. Geom., 2009, pp. 163-166.
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Michael A. Bender, Sándor P. Fekete, Tom Kamphans, Nils Schweer
Maintaining Arrays of Contiguous Objects
Proc. 17th Internat. Sympos. Fund. Comput. Theory,
Lecture Notes Comput. Sci. 5699, 2009, pp. 14-25.
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Sándor P. Fekete, Tom Kamphans, Nils Schweer
Online Square Packing
Proc. 20th Algorithms and Data Structure Symposium (WADS),
Lecture Notes Comput. Sci. 5664, Springer, 2009, pp. 302-314.
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Sándor P. Fekete, Tom Kamphans, Nils Schweer
Online Square Packing
Abstracts 25th European Workshop Comput. Geom., 2009, pp. 269-272.
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Ali Ahmadinia, Josef Angermeier, Sándor P. Fekete, Diana Göhringer, Tom Kamphans, Dirk Koch, Mateusz Majer, Nils Schweer, Jürgen Teich, Christopher Tessars, Jan C. van der Veen
ReCoNodes - Optimization Methods for Module Scheduling and Placement on Reconfigurable Hardware Devices
In Dynamically Reconfigurable Systems: Architectures, Design Methods and Applications,
edited by Marco Platzner, Jürgen Teich, Norbert Wehn, Springer, 2009, pp. 199-221.
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Rudolf Fleischer, Tom Kamphans, Rolf Klein, Elmar Langetepe, Gerhard Trippen
Competitive online approximation of the optimal search ratio
Siam J. Comput., pp. 881-898, 2008.
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Daniel Herrmann, Tom Kamphans, Elmar Langetepe
Exploring Simple Triangular and Hexagonal Grid Polygons Online
Abstracts 24th European Workshop Comput. Geom., 2008, pp. 177-180.
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Rolf Klein, Tom Kamphans
Der Pledge-Algorithmus: Wie man im Dunkeln aus einem Labyrinth entkommt
In Taschenbuch der Algorithmen,
edited by Berthold Vöcking, Helmut Alt, Martin Dietzfelbinger, Rüdiger Reischuk, Christian Scheideler, Heribert Vollmer, Dorothea Wagner, eXamen.press , Springer, 2008, pp. 75-81.
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Tom Kamphans, Elmar Langetepe
Leaving an unknown maze using an error-prone compass
Accepted for Internat. J. Comput. Geom. Appl., 2008.
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Josef Angermeier, Sándor P. Fekete, Tom Kamphans, Dirk Koch, Nils Schweer, Jürgen Teich, Christopher Tessars, Jan C. van der Veen
No-Break Dynamic Defragmentation of Reconfigurable Devices
Proc. Internat. Conf. Field Program. Logic Appl., 2008, pp. 113-118.
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Daniel Herrmann, Tom Kamphans, Elmar Langetepe
Exploring Simple Triangular and Hexagonal Grid Polygons Online
Technical Report 007, Department of Computer Science I, University of Bonn, 2007.
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Bernd Brüggemann, Tom Kamphans, Elmar Langetepe
Escaping from a Labyrinth with One-way Roads for Limited Robots
Abstracts 3rd European Conf. Mobile Robots, 2007.
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Bernd Brüggemann, Tom Kamphans, Elmar Langetepe
Leaving an Unknown Maze with One-Way Roads
Abstracts 23rd European Workshop Comput. Geom., 2007, pp. 90-93.
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Bernd Brüggemann, Tom Kamphans, Elmar Langetepe
Leaving an Unknown Maze with One-Way Roads
Abstracts 12th European Conf. Operational Research, 2007, pp. 140.
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Andrea Eubeler, Rudolf Fleischer, Tom Kamphans, Rolf Klein, Elmar Langetepe, Gerhard Trippen
Searching for rays and lower bound constructions
Abstracts 12th European Conf. Operational Research, 2007, pp. 65.
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Andrea Eubeler, Rudolf Fleischer, Tom Kamphans, Rolf Klein, Elmar Langetepe, Gerhard Trippen
Competitive Online Searching for a Ray in the Plane
Robot Navigation,
Dagstuhl Seminar Proceedings , Internationales Begegnungs- und Forschungszentrum für Informatik (IBFI), Schloss Dagstuhl, Germany, 2006.
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Birgit Engels, Tom Kamphans
Randolph's Robot Game is NP-hard!
Electronic Notes in Discrete Mathematics 25, pp. 49-53, 2006.
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Birgit Engels, Tom Kamphans
On the Complexity of Randolph's Robot Game
Technical Report 005, Department of Computer Science I, University of Bonn, 2005.
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Tom Kamphans, Elmar Langetepe
Optimal competitive online ray search with an error-prone robot
Technical Report 003, Department of Computer Science I, University of Bonn, 2005.
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Christian Icking, Tom Kamphans, Rolf Klein, Elmar Langetepe
Exploring grid polygons online
Technical Report 001, Department of Computer Science I, University of Bonn, 2005.
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Andrea Eubeler, Rudolf Fleischer, Tom Kamphans, Rolf Klein, Elmar Langetepe, Gerhard Trippen
Competitive Online Searching for a Ray in the Plane
Abstracts 21st European Workshop Comput. Geom., 2005, pp. 107-110.
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Christian Icking, Tom Kamphans, Rolf Klein, Elmar Langetepe
Exploring simple grid polygons
11th Internat. Comput. Combin. Conf.,
Lecture Notes Comput. Sci. 3595, Springer, 2005, pp. 524-533.
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Tom Kamphans, Elmar Langetepe
Optimal competitive online ray search with an error-prone robot
Proc. 4th Internat. Workshop Efficient Experim. Algorithms,
Lecture Notes Comput. Sci. 3503, Springer, 2005, pp. 593-596.
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Tom Kamphans, Elmar Langetepe
On optimizing multi-sequence functionals for competitive analysis
Abstracts 21st European Workshop Comput. Geom., 2005, pp. 111-114.
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Rudolf Fleischer, Tom Kamphans, Rolf Klein, Elmar Langetepe, Gerhard Trippen
Competitive online approximation of the optimal search ratio
Proc. 12th Annu. European Sympos. Algorithms,
Lecture Notes Comput. Sci. 3221, Springer-Verlag, 2004, pp. 335-346.
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Rudolf Fleischer, Tom Kamphans, Rolf Klein, Elmar Langetepe, Gerhard Trippen
Competitive search ratio of graphs and polygons
Abstracts 20th European Workshop Comput. Geom.,
Universidad de Sevilla, 2004, pp. 127-130.
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Tom Kamphans, Elmar Langetepe
Finding a door along a wall with an error afflicted robot
Abstracts 20th European Workshop Comput. Geom.,
Universidad de Sevilla, 2004, pp. 143-146.
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Tom Kamphans, Elmar Langetepe
The Pledge Algorithm Reconsidered under Errors in Sensors and Motion
Proc. of the 1th Workshop on Approximation and Online Algorithms,
Lecture Notes Comput. Sci. 2909, Springer, 2003, pp. 165-178.
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Christian Icking, Thomas Kamphans, Rolf Klein, Elmar Langetepe
On the competitive complexity of navigation tasks
Sensor Based Intelligent Robots,
Lecture Notes Comput. Sci. 2238, Springer, Berlin, 2002, pp. 245-258.
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Tom Kamphans, Elmar Langetepe
Online Bewegungsplanung für Roboter
Vorlesungsskript, Universität Bonn, Institut für Informatik, 2002.
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Tom Kamphans, Rolf Klein
Bewegungsplanung für Roboter
Vorlesungsskript, Universität Bonn, Institut für Informatik, 2001.
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Christian Icking, Thomas Kamphans, Rolf Klein, Elmar Langetepe
Exploring an Unknown Cellular Environment
Abstracts 16th European Workshop Comput. Geom.,
Ben-Gurion University of the Negev, 2000, pp. 140-143.
Software
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Tom Kamphans, Michael Stelzer
SPUL: Shortest Path with Unique Labels
C++ program, 2008.
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Ulrich Handel, Tom Kamphans, Elmar Langetepe, Wolfgang Meiswinkel
PolyRobot - an environment for simulating strategies for robot navigation in polygonal scenes
Java Applet, 2002.
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Ulrich Handel, Christian Icking, Tom Kamphans, Elmar Langetepe, Wolfgang Meiswinkel
GridRobot - an environment for simulating exploration strategies in unknown cellular areas
Java Applet, 2000.
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Geometry-Lab
Photographs
Some of my talks
- Robot Swarms for Exploration and Triangulation of Unknown Environments, FRONTS 2nd Year General Assembly Meeting, Feb. 01, 2010, Barcelona, Spain:
Animated slides (Apple Keynote file),
Printable slides (PDF)
- Project ReCoNodes, Project Summary, Sept. 25, 2009, Karlsruhe, Germany:
Animated slides (Apple Keynote file),
Printable slides (PDF)
- Maintaining Arrays of Contiguous Objects, FCT 2009, Wrocƚaw, Poland
- Exploring Simple Triangular and Hexagonal Grid Polygons Online, EuroCG 2008, Nancy, France (Animated slides, Printable slides with notes)
- Leaving an Unknown Maze with One-Way Roads, EURO 2007, Prag
- PhD Talk 04.04.2006 (Animated slides, Printable slides with notes)
- Exploring Simple Grid Polygons, Cocoon 2005, Kunming, China (Animated slides, Printable slides with notes)
- Exploring Simple Grid Polygons, Bonn, July 2005
- Optimal Competitive Online Ray Search with an Error-Prone Robot, WEA '05, Santorini, Greece
- The Pledge Algorithm Reconsidered under Errors in Sensors and Motion, WAOA 2003, Budapest
Master thesis
Former Affiliations
04/2011 - 09/2011
HTW Berlin,
Fachbereich I
11/2007 - 01/2011
Braunschweig University,
Algorithms Group
08/2000 - 10/2007
University of Bonn,
Institute of Computer Science I
11/1998 - 07/2000
University of Hagen,
Praktische Informatik VI